HORDB

ID: hor002466
Uniprot ID: Q10998(87-99)
Protein name: Cerebral peptide 1
Gene name: NA
Organism: Aplysia californica (California sea hare)
Family: NA
Source: animal
Expression: Cerebral peptide 1 is expressed in the cerebral, pedal and buccal ganglia and B1 and B2 neurons. APGW-amide is expressed in buccal ganglia and several neurons.
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: NA
GO CC: GO:0005576 extracellular region

Sequence: FSGLMSEGSSLEA
Length: 13(87-99)
Propeptide: MLLAKISVVVLLLAIDGTSSSESTDNVVLSSSPDSQKAATSRHKRAPGWGKRSSLNDEDLFADSDSAQELLDSVAALKRAPGWGKRFSGLMSEGSSLEAKRAPGWGKRGQEIDVDEDGSEQEKRAPGWGKRAPGWGKRAPGWGKRAPGWGKRAPGWGKRAPGWGKRSGGDYCETLEKMVDAYIYKAVEVDSRRLADCGSGEGTNEPFRK
Signal peptide: MLLAKISVVVLLLAIDGTSS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002466_AF2.pdb

hor002466_ESM.pdb

Mass:	152864	Formula:	C55H87N13O22S
Absent amino acids:	CDHIKNPQRTVWY	Common amino acids:	S
pI:	3.61	Basic residues:	0
Polar residues:	6	Hydrophobic residues:	4
Hydrophobicity:	23.85	Boman Index:	-836
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	67.69
Instability Index:	7266.15	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 8844763
Title: Purification, Primary Structure, and Neuronal Localization of Cerebral Peptide 1 From Aplysia